Comparative study of second generation anti-histamine (Cetrizine) alone v/s antihistamine with leukotriene receptor antagonist (Monstelukast sodium) in the treatment of allergic rhinitis

Abstract

Allergic rhinitis is one of the significant public health problem in which nasal congestion, sneezing, nasal pruritus and rhinorrhea are most common problems faced by patients which not only exacerbate work performance but also their quality of life. Allergic rhinitis prevalence has been increased rapidly in industrialized countries. Present study was carried out among allergic rhinitis patients visiting Lahore General Hospital, Lahore and different clinics of Lahore. Total 200 patients divided into two equal groups (Group-A and Group-B) were included in this study. Group-A was treated with cetirizine alone while Group-B was treated with cetirizine along with montelukast. Results were obtained as relief of symptoms. Data was analyzed by statistical software SPSS (Statistical Package for Social Sciences) version 19.0. Results concluded that combination of cetirizine + montelukast is more beneficial in allergic rhinitis.