Antibacterial and wound healing potential of kinnow (Citrus Mandarin) peel’s essential oil

Abstract

Citrus mandarin commonly named as kinnow is most widely produced and well cultivated in the Pakistan. The peel of Citrus fruit is much more effective as that of the fruit because it is composed of limonene which plays an important role therapeutically. Now a day in Pakistan even throughout the country the Citrus fruits are used for medicinal purpose because it has great efficacy and less adverse effect. The Citrus mandarin belongs to the family Rutaceae that has a great antioxidant activity, anti-inflammatory activity, anti-diabetic activity, anti- microbial activity and cytotoxic activity. The essential oil was extracted through the process of hydro-distillation at boiling temperature. The objective of this study is to check the wound healing potential, antimicrobial activity, GC-MS analysis, and skin irritation of the essential oil of kinnow peel. The wound healing activity of kinnow peel essential oil was within 8 days, whereas antimicrobial activity was checked against gram positive (Staphylococcus aureus) and gram-negative bacteria (Escherichia coli). GC-MS analysis showed that essential oil composed of limonene, hexanal, decanal, octanal, hexa-decanal and other constituents. Limonene is greater and chief constituent of essential oil of kinnow. The skin irritation showed that it is nontoxic and nonirritant to the skin of rabbit.