Polymeric nanoparticles as potential source to overcome antimicrobial resistance

Abstract

Antimicrobial resistance is one of the top three health issues in the world as many of the existing antimicrobial therapies have become ineffective due to resistance produced by different organisms. The need is to develop more effective strategies to overcome this issue. Nanoparticles based therapy and drug delivery have made a breakthrough. Polymeric nanoparticles including PLGA, PLA, Chitosan etc. have an effective mechanism to combat this issue with their antimicrobial properties and they also make many drug therapies effective by efficient drug delivery system. They have many applications in medical field including cancer therapy and vaccine delivery but their role in antimicrobial therapy is of utmost importance as the antimicrobial resistance issue is critical and requires effective alternate therapies, so that resistance to sensitive bacteria can be prevented.